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Evaluating emotional sensitivity and tolerance factors in the prediction of panic-relevant responding to a biological challenge
Authors:Amanda Kutz  Erin Marshall  Amit Bernstein  Michael J Zvolensky
Institution:1. University of Houston, Department of Psychology, 126 Heyne Building, Houston, TX 77024, United States;2. The University of Texas MD Anderson Cancer Center, Department of Behavioral Science, 1155 Pressler Street, Houston, TX 77030, United States;3. Department of Preventive Medicine, University of Southern California Keck School of Medicine, 2250 Alcazar St., CSC 240, Los Angeles, CA 90033, United States;4. Department of Psychology, University of Southern California, 2250 Alcazar St., CSC 240, Los Angeles, CA 90033, United States;5. Syracuse University, Department of Psychology, 506 Huntington Hall, Syracuse, NY 13244, United States;6. Florida State University, Department of Psychology, 1107 W Call St., Tallahassee, FL 32304, United States;1. University of California, San Diego, Department of Psychiatry, 9500 Gilman Drive, MC 0405, La Jolla, CA 92093, United States;2. Yale University School of Medicine, Department of Psychiatry, 300 George St., Suite 901, New Haven, CT 06511, United States;1. Department of Preventive Medicine, University of Southern California, Los Angeles, CA, United States;2. Department of Psychology, University of Southern California, Los Angeles, CA, United States;3. Department of Psychology, Florida State University, Tallahassee, FL, United States;4. Department of Psychology, University of Houston, Houston, TX, United States;5. Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Abstract:The current study investigated anxiety sensitivity, distress tolerance (Simons & Gaher, 2005), and discomfort intolerance (Schmidt, Richey, Cromer, & Buckner, 2007) in relation to panic-relevant responding (i.e., panic attack symptoms and panic-relevant cognitions) to a 10% carbon dioxide enriched air challenge. Participants were 216 adults (52.6% female; Mage = 22.4, SD = 9.0). A series of hierarchical multiple regressions was conducted with covariates of negative affectivity and past year panic attack history in step one of the model, and anxiety sensitivity, discomfort intolerance, and distress tolerance entered simultaneously into step two. Results indicated that anxiety sensitivity, but not distress tolerance or discomfort intolerance, was significantly incrementally predictive of physical panic attack symptoms and cognitive panic attack symptoms. Additionally, anxiety sensitivity was significantly predictive of variance in panic attack status during the challenge. These findings emphasize the important, unique role of anxiety sensitivity in predicting risk for panic psychopathology, even when considered in the context of other theoretically relevant emotion vulnerability variables.
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