State of the Art of Combined Heart-Lung Transplantation for Advanced Cardiac and Pulmonary Dysfunction |
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Authors: | Jay J. Idrees Gösta B. Pettersson |
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Affiliation: | 1.Department of Thoracic and Cardiovascular Surgery,Heart and Vascular Institute, Cleveland Clinic,Cleveland,USA;2.Department of Quantitative Health Sciences,Research Institute, Cleveland Clinic,Cleveland,USA |
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Abstract: | Over the last several decades, significant advances and improvements in care of transplant patients have resulted in markedly improved outcomes. A number of options are available for patients with advanced cardiopulmonary dysfunction requiring transplantation. There is a debate about when isolated heart or isolated lung transplantation is no longer possible or advisable and combined heart-lung transplantation is justified. Organ availability and allocation severely limit the latter option to very few well-selected patients. We review practice patterns, trends, and outcomes after triple-organ heart-lung transplant (HLTx) worldwide, as well as our own experience with heart-lung transplant in the modern era. |
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