超声诊断颈动脉粥样硬化与血清胆红素的关系

目的 :探讨超声诊断颈动脉粥样硬化 (CAS)与胆红素之间的关系。方法 :依照颈动脉超声检测结果选择6 0例 CAS患者及 6 0名健康人对照 ,测定血清胆红素 ,总胆固醇 (TC)、甘油三酯 (TG)及高密度脂蛋白胆固醇 (HDL-C) ,低密度脂蛋白胆固醇 (L DL - C)。结果 :CAS组患者总胆红素 (TBIL )、直接胆红素 (DBIL )较健康对照组均明显降低 (P<0 .0 5 ) ,甘油三酯 (TG)、总胆固醇 (TC)、低密度脂蛋白胆固醇 (L DL- C)较对照组显著升高 (P<0 .0 5 )。结论 :血清胆红素影响血脂代谢 ,血清胆红素浓度低下可能导致脂质代谢紊乱 ,并加速 CAS进程。

The Relation between Serum Bilirubin and Carotid Artery Arthe rosclerosis Diagnosed by Ultrasound

Objective To investigate the relation be tween se rum bilirubin and carotid artery artherosclerosis diagnosed by ultrasound. Method According to the result of ultrasonography ,we choosed 60 patient s with carotid artery artherosclerosis and 60 health persons .The serum of 120 p atients were examined for the value of bilirubin, total cholesterol(TC),triglyce rides(TG),high density lipoprotein-cholesterol (HDL-C),and low density lipopro te in-cholesterol (LDL-C).Results Patients with CAS had a significa nt ly lower serum total bilirubin(TBIL) and direct bilirubin(DBIL) concentration than those of controls(P<0.05).At the same time, there were si gnificantly higher serum concentration of TG、TC and LDL-C in patients with CA S (P<0.05) than those of controls.Conclusion Biliru bin affects the metabolism of blood lipids. The low concentration of bilirubin p robably brings about a disorder of blood lipids and accelerates the course of CA S.