| 岩黄连总碱对小鼠急性化学性肝损伤的保护作用研究 |
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| 引用本文： | 周劲光. 岩黄连总碱对小鼠急性化学性肝损伤的保护作用研究[J]. 中国当代医药, 2010, 17(27): 29-30 |
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| 作者姓名： | 周劲光 |
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| 作者单位： | 河南大学淮河医院临床教学办&药剂科,河南开封,475000 |
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| 摘 要： | 目的：研究岩黄连总碱对CCl4所致小鼠急性肝损伤的保护作用。方法：腹腔注射给予CCl4致小鼠急性肝损伤,通过灌胃给药观察岩黄连总碱对其保护作用。结果：岩黄连总碱可明显降低CCl4因素所致急性肝损伤小鼠血清AST、ALT的含量。结论：岩黄连总碱对CCl4所致小鼠急性肝损伤具有保护作用。
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| 关 键 词： | 岩黄连总碱 四氯化碳 肝损伤 |
Study of hepatoprotective effect of the total alkaloids from Corydalis saxicola bunting of the acute chemical hepatic injury model mice |
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| ZHOU Jinguang. Study of hepatoprotective effect of the total alkaloids from Corydalis saxicola bunting of the acute chemical hepatic injury model mice[J]. http://www.botanicus.org/, 2010, 17(27): 29-30 |
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| Authors: | ZHOU Jinguang |
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| Affiliation: | ZHOU Jinguang (Department of BST＆Pharmacy,the Affiliated Huaihe Hospital of Henan University,Henan Province,Kaifeng 475000,China) |
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| Abstract: | Objective： To study the protective effect of the total alkaloids from Corydalis saxicola bunting of the acute hepatic injury model mice caused by carbon tetrachloride.Methods： The protective effect of the total alkaloids from Corydalis saxicola bunting by intragastric administration against peritoneal injection CCl4-induced hepatic injury in mice were investigated. Results： The contents of serum transaminases（ALT and AST） of medication administration team compare with model team was degraded. Conclusion： The results indicate that the CCl4-induced hepatic injury of mouse was protected significantly. |
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| Keywords: | The total alkaloids from Corydalis saxicola Bunting CCl4 Hepatic injury |
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