体外循环内直视先心纠治术对心肌肌钙蛋白的影响及意义

目的：研究心脏不停跳心内直视先心纠治术对心肌肌钙蛋白（ｃＴｎ－Ｔ）的影响及意义。方法：检测１６例体外循环心脏不停跳心内直视先心纠治术治疗患者术前、术中及术后血清ｃＴｎ－Ｔ及肌酸磷酸激酶同功酶（ＣＫ－ＭＢ），并进行对比分析。结果：血清ｃＴｎ－Ｔ明显增高，于停机时达到最高峰，并持续高于术前水平至术后２周。ＣＫ－ＭＢ于术后２ｈ达最高峰，术后１周即恢复至术前水平。结论：体外循环心脏不停跳先心纠治术中，血清

THE SIGNIFICANCE AND EFFECTS ON CARDIAC TROPONIN T DURING CARDIAC SURGERY WITH COMPULMONARY BYPASS IN PATIENTS OF CONGENITAL HEART DISEASE

Objective:To study the effects and significance on cardiac troponin T(cTn T) during cardiac surgery with compulmonary bypass (CPB) in patients with congenital heart disease (CHD) Methods:During the perioperative term,the serum concentration of cTn T and creatine kinase MB(CK MB) were measured in 16 patients with CHD who had undergone cardiac surgery with CPB Results:cTn T came to its peak while stopping CPB and kept a higher level than preoperative level for two weeks postoperatively,however,CK MB reached its peak in 24 hours post operative course and returned to its preoperative level for 7 days postoperatively Conclusion:cTn T may be an useful and valuable indicator in evaluating the degree of myocardial cell damage and myocardial protection,and its censitivity,specificity and lasting time are better than cardiac erzymes