宁波某地区肺炎支原体与其他呼吸道病原体混合感染观察

目的 探讨宁波某地区儿童肺炎支原体与其他呼吸道病原体的交叉感染的情况,为儿童呼吸道疾病的诊治提供参考.方法 入院用日本富士被动颗粒凝集法检测血清肺炎支原体抗体IgM为阳性患儿337例,同时用郑州安图间接免疫荧光法检测甲型流感病毒抗体IgM（INFA）、乙型流感病毒抗体IgM（INFB）、嗜肺军团菌抗体IgM（LP）、副流感病毒1、2、3型抗体IgM（PIV）、腺病毒抗体IgM（ADV）、呼吸道合胞病毒抗体IgM （RSV）、肺炎衣原体抗体IgM （Cpn）.结果 337例MP-IgM阳性患儿混合感染其他呼吸道病原体比率为60.5％ （204/337）.其中混合感染一种病原体比率为37.4％（126/337）,以INFB为主;混合感染两种病原体比率为16.9％（57/337）,以INFB＋ADV和INFB＋PIV为主;混合感染三种及以上病原体比率为6.2％ （21/337）,以INFB＋ PIV＋ADV为主,混合感染均以24岁为主.结论 本地区MP患儿与其他呼吸道病原体交叉感染率相对较高,并以MP＋INFB模式为主,应对此加以重视.

An observation of mycoplasma pneumoniae and mixed infected with other respiratory pathogen in a region of Ningbo

Objective To discuss the circumstance of mycoplasma pneumoniae（MP） and mixed in- fected with other respiratory pathogens of children in a region of Ningbo, providing the reference for the diagnosis and treatment of childhood respiratory disease. Methods The MP IgM were positive in 337 children by the detection of Japanese Fushi passive agglutination method. Mean- while, Zhengzhou Antu indirect immunofluorescence was used to detect the influenza a virus IgM （INFA）, influenza B virus IgM （INFB）, eosinophilic lung legionella IgM （LP）, deputy flu virus type 1, 2, 3, IgM （PIV）, adenovirus （ADV）, respiratory syncytial virus IgM （RSV）. Results The ratio of MP-IgM mixed infected with other respiratory pathogen was 60.5 % （204/337） in 337 children. Among them, the ratio of MP-IgM mixed infected with one pathogen was 37.4% （126/337）, the major was INFB; Mixed infected with two kinds of pathogens was 16.9% （57/ 337）, the major were INFB ＋ ADV and INFB ＋ PIV; Mixed infected with three or more patho- gens was 6.2% （21/337）, the major were INFB＋PIV＋ADV. Moreover, the mixed infection was given priority to 2-4 years old children. Conclusion The ratio of children mixed infected with MP and other respiratory pathogens was relatively higher, the major model was MP ＋ INFB, which should be paid attention to.