胶原酶溶解术与射频热凝术治疗颈椎间盘突出症的对照研究

目的：比较胶原酶化学溶解术与射频热凝术治疗颈椎间盘突出症的临床疗效。方法158例颈椎间盘突出症患者分为2组，采用射频热凝术治疗72例；采用胶原酶化学溶解术治疗86例。于术后1周、1个月、3个月、6个月随访，根据MacNab疗效评定标准和VAS评分法，对治疗后优良率、总有效率和疼痛程度进行比较。结果胶原酶优良率及有效率明显高于射频组（P〈0.05）；VAS评分后，术后1周，射频组优于胶原酶组（P〈0.01）。但6个月后胶原酶组优于射频组（P〈0.05）。结论射频热凝术和胶原酶溶解术均为治疗颈椎间盘突出症的有效疗法。

Comparison of the effects of collagenase chemonucleolysis and radiofrequency thermocoagula-tion in the treatment of cervical intervertebral disc herniation

Objective To compare and evaluate the effect of collagenase chemonucleolysis （CNL）and radiofrequency thermocoagulation in the treatment of cervical intervertebral disc hernia-tion. Methods 158 patients with cervical intervertebral disc herniation were divided into two groups based on the treatment they received.72 patients in A group were treated by radiofrequency thermocoagulation,and 86 patients in B group were treated by CNL. The total effective rate and pain degree were assessed according to MacNab criteria and VAS scoring after follow-up for one week, one month, three months and six months. Results The assessment of MacNab showed the effect of group B was better than group A after surgery （P〈0.05）. One week after treatment,the as-sessment of VAS showed that the effect of group A was better than group B after surgery （P〈0.01）, but 6 months after treatment, the effect of group B was better than group A （P〈0.05）. Conclusion The radiofrequency thermocoagulation and CNL are both effective in the treatment of cervical inter-vertebral disc herniation.