β射线局部照射对冠状动脉弥漫性支架内再狭窄的疗效

目的：探讨β射线(^90Sr/^90Y)对冠状动脉(简称冠脉)弥漫性支架内再狭窄的疗效。方法:39例经皮冠脉介入术(PCI)及支架置入术后支架内再狭窄患者，随机分为支架内放射治疗组(治疗组)18例及单纯球囊组(对照组)21例。2组患者再狭窄病变先经充分球囊扩张，治疗组用Beta-Cath系统进行冠脉内放射治疗。术后随访9个月。结果:治疗组1例(5．6％)研究段血管再狭窄，对照组有8例(38．1％)再狭窄，两组间差异有显著性(P=0．006)。结论:β射线治疗冠脉弥漫性支架内再狭窄安全、有效、可行。

Clinical effects of intracoronary brachytherapy on diffuse in-stent restenosis after coronary angioplasty

Objective To investigate the effect of intracoronary brachytherapy using 90 Sr/ 90 Y on in-stent restenosis in patients with coronary disease. Methods Thirty-nine patients (male 29 ,female 10) with in-stent restenosis after percutaneous coronary intervention (PCI) were studied. The patients were divided randomly into two groups: single-balloon group(21 cases,control group) and brachytherapy group(18 cases,treatment group). All the lesions were treated with balloon angioplasty satisfactorily. After that the patients in treatment group took a brachytherapy using the Beta-Cath system(Novoste). After the operation,there was a 9-months follow-up. Results Within the follow-up,one case (5.6%) in treatment group was found to be with in-stent restenosis and 8 cases(38.1%) in control group. There was significant difference between the two groups(P=0.006). Conclusion The brachytherapy using 90 Sr/ 90 Y after balloon angioplasty is safe,effective and feasible for containing diffuse in-stent restenosis in patients.