| 四膜虫对8-MOP处理的生长反应—真核原生生物四膜虫DNA损伤修复机理的研究(Ⅰ) |
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| 引用本文： | 夏凤琴,Peter E Nielsen. 四膜虫对8-MOP处理的生长反应—真核原生生物四膜虫DNA损伤修复机理的研究(Ⅰ)[J]. 吉林大学学报(医学版), 1991, 0(5) |
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| 作者姓名： | 夏凤琴 Peter E Nielsen |
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| 作者单位： | 白求恩医科大学许射医学研究所放射生物教研室 Institute(夏凤琴)，Biochem.B.Panum Copenhagen(Peter E Nielsen) |
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| 摘 要： | 本文研究了四膜虫在8—MOP和紫外线(波长为365nm)照射联合处理以后细胞的生长反应。我们观察到被处理的细胞或暂时性受抑(<1μg—8MOP/ml细胞悬液)或永久性受抑(>1μg 8—MOP/1ml)细胞悬液)。暂时性受抑的细胞,在经过一定的迁延期以后可恢复其生长能力,其迁延期长短与8—MOP的剂量有关。
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| 关 键 词： | 四膜虫 8—MOP 紫外线照射 细胞生长反应 |
GROWTH RESPONSE OF TETRAHYMENA THERMOPHILA TO 8-MOP TREATMENT |
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| Xia Fengqin,Peter E Nielsen. GROWTH RESPONSE OF TETRAHYMENA THERMOPHILA TO 8-MOP TREATMENT[J]. Journal of Jilin University: Med Ed, 1991, 0(5) |
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| Authors: | Xia Fengqin Peter E Nielsen |
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| Abstract: | Protozoan Tetrahymena thermophila was treated with 8-MOP in combination with 365 nm ultraviolet irradiation, and the growth response of the cells was studied. This treatment resulted in either a temporary inhibition (1 μg of 8-MOP/ml) or a permanent inhibition of the cell proliferation (1 μg of 8-MOP/ml). Those cells which were temporarily inhibited regained their proliferability following a lag-period. The duration of the temporary inhibition of cellular multiplication by pso-ralen was dose-dependent with a linear correlation. |
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| Keywords: | Tetrahymena thermophila 8-MOP Ultraviolet irradiation Growth response of cells |
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