Gadofluorine M-enhanced MRI shows involvement of circumventricular organs in neuroinflammation |
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| Authors: | Eva Wuerfel Carmen Infante-Duarte Robert Glumm Jens T Wuerfel |
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| Affiliation: | 1.Experimental and Clinical Research Center,Charité - University Medicine Berlin,Berlin,Germany;2.Department of Pediatrics,University Luebeck,Luebeck,Germany;3.Institute of Neuroradiology,University Luebeck,Luebeck,Germany |
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| Abstract: | Background Circumventricular organs (CVO) are cerebral areas with incomplete endothelial blood-brain barrier (BBB) and therefore regarded as "gates to the brain". During inflammation, they may exert an active role in determining immune cell recruitment into the brain. |
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