| 再次肾移植的临床特点及治疗体会 |
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| 引用本文： | 张勇,靳风烁,李黔生,李彦峰,张克勤,聂智林. 再次肾移植的临床特点及治疗体会[J]. 第三军医大学学报, 2008, 30(12): 1200-1202 |
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| 作者姓名： | 张勇 靳风烁 李黔生 李彦峰 张克勤 聂智林 |
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| 作者单位： | 第三军医大学大坪医院野战外科研究所泌尿外科,重庆,400042 |
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| 摘 要： | 目的 分析影响再次移植肾存活率的各种因素,提高再次移植肾的长期存活率.方法 对39例再次肾移植进行回顾性分析.结果 再次肾移植术后1、3、5年移植肾存活率显著低于初次肾移植(分别为76.5%、64.2%、56.5%和87.1%、75.1%、68.2%, P<0.05);群体反应性抗体(PRA)阳性受者术后急性排斥反应发生率高于PRA阴性受者,使用抗体诱导治疗患者术后急性排斥反应发生率低于未用抗体诱导治疗患者.是否切除失功肾对再次移植肾存活率无明显影响.结论 再次移植肾存活率明显低于首次移植.个体高免疫状态是再次肾移植的危险因素,必须更加严格地进行组织配型,进行抗体诱导治疗有利于再次移植肾的存活.如没有排斥反应及并发症的发生,不主张切除原移植肾.
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| 关 键 词： | 肾移植 存活率 排斥反应 |
| 文章编号： | 1000-5404(2008)12-1200-03 |
| 修稿时间： | 2008-03-12 |
Clinical features and treatment of renal retransplantation |
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| ZHANG Yong,JIN Feng-shuo,LI Qian-sheng,Li Yan-feng,ZHANG Ke-qin,NIE Zhi-lin. Clinical features and treatment of renal retransplantation[J]. Acta Academiae Medicinae Militaris Tertiae, 2008, 30(12): 1200-1202 |
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| Authors: | ZHANG Yong JIN Feng-shuo LI Qian-sheng Li Yan-feng ZHANG Ke-qin NIE Zhi-lin |
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| Affiliation: | ZHANG Yong,JIN Feng-shuo,LI Qian-sheng,Li Yan-feng,ZHANG Ke-qin,NIE Zhi-lin(department of urology,Daping Hospital,Third Military Medical University,Chongqing 400042,China) |
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| Abstract: | Objective To analyze the factors affecting the kidney retransplantation and to improve the survival rate in long term.Methods Retrospective analysis of 39 cases with kidney retransplantation.Results Survival rates of the retransplantation group at 1,3,5 year were 76.5%,64.2%,56.5% respectively,while those in the control group were 87.1%,75.1%,68.2%.The differences in grafting survival rates between the 2 groups were significant(P<0.05).Higher incidences of acute rejection were found in patients with positiv... |
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| Keywords: | kidney transplantation survival rate rejection |
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