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A population-based follow-up study on gallstone disease among type 2 diabetics in Kinmen, Taiwan |
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| Authors: | Tung Tao-Hsin Ho Hsiao-Man Shih Hui-Chuan Chou Pesus Liu Jorn-Hon Chen Victor-T K Chan De-Chuan Liu Chi-Ming |
| Affiliation: | 1. Cheng Hsin Rehabilitation Medical Center,Taipei, Taiwan; National Taipei College of Nursing, Taipei,Taiwan, China 2. Department of Mathematics and Science Education, National Taipei Teachers College, Taipei, Taiwan,China 3. Department of Nursing, Kaohsiung Military General Hospital, Kaohsiung, Taiwan; I-Shou University,Kaohsiung, Taiwan, China 4. Community Medicine Research Center & Institute of Public Health, National Yang-Ming University, Taipei, Taiwan,China 5. Cheng Hsin Rehabilitation Medical Center; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, China 6. Cardinal Tien Hospital; College of Medicine,Fu-Jen Catholic University; National Defence Medicine Center,Taipei, Taiwan, China 7. Division of General Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan,China 8. Cheng Hsin Rehabilitation Medical Center, Taipei,Taiwan; Community Medicine Research Center and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan,China |
| Abstract: | AIM: To assess the incidence of and risk factors for gallstone disease (GSD) among type 2 diabetics in Kinmen, Taiwan. METHODS: A screening program for GSD was performed by two specialists who employed real-time abdominal ultrasound to examine the abdominal region after patients had fasted for at least eight hours. Screening, which was conducted in 2001, involved 848 patients diagnosed with type 2 diabetes. After exclusion of 63 subjects with prevalent GSD, 377 participants without GSD were invited in 2002 for a second round of screening. A total of 281 (74.5%) subjects were re-examined. RESULTS: Among the 281 type 2 diabetics who had no GSD at the first screening, 10 had developed GSD by 2002. The incidence was 3.56% per year (95%CI: 1.78% per year-6.24% per year). Using a Cox regression model, age (RR = 1.07, 95% CI: 1.00-1.14), waist circumference (RR = 1.12, 95% CI: 1.01-1.29), and ALT (RR = 1.13, 95%CI: 1.01-1.26) appeared to be significantly correlated with development of GSD. CONCLUSION: Older age is a known risk factor for the development of GSD. Our study shows that greater waist circumference and elevated ALT levels are also associated with the development of GSD among type 2 diabetics in Kinmen. |
| Keywords: | Type 2 diabetes Gallstone disease Incidence density Population-based study |
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