| 10%苯巴比妥钠注射液贮存期预测 |
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| 引用本文： | 温玉麟,王志礼,庞辉,刘仁宽.10%苯巴比妥钠注射液贮存期预测[J].药学学报,1983,18(6):478-480. |
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| 作者姓名： | 温玉麟 王志礼 庞辉 刘仁宽 |
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| 作者单位： | 天津人民制药厂;*沈阳药学院 |
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| 摘 要： | The shelf-life of 10% sodium phenobarbital injection(containing propylene glycol 60%) has been predicted by accelerated stability test with the classical isothermal method (at 100, 90, 80 and 70℃). The data was treated with regressive calculation, and the shelf-life calculated with three different methods (regressive calculation, average activation energy calculation and graphical plotting).The values obtained from these three methods were approximately equal, and also coincided with the value obtained from samples reserved for observation at room temperature. The shelf-life was 1.05 years at 25℃, and 2.03 years at 20℃.
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| 关 键 词： | 苯巴比妥钠注射液 贮存期 |
| 收稿时间： | 1982-07-13 |
PREDICTION OF THE SHELF-LIFE OF 10% SODIUM PHENOBARBITAL INJECTION |
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| WEN Yu-lin,WANG Zhi-li,PANG Hui and LIU Ren-kuan.PREDICTION OF THE SHELF-LIFE OF 10% SODIUM PHENOBARBITAL INJECTION[J].Acta Pharmaceutica Sinica,1983,18(6):478-480. |
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| Authors: | WEN Yu-lin WANG Zhi-li PANG Hui and LIU Ren-kuan |
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| Abstract: | The shelf-life of 10% sodium phenobarbital injection(containing propylene glycol 60%) has been predicted by accelerated stability test with the classical isothermal method (at 100, 90, 80 and 70℃). The data was treated with regressive calculation, and the shelf-life calculated with three different methods (regressive calculation, average activation energy calculation and graphical plotting).The values obtained from these three methods were approximately equal, and also coincided with the value obtained from samples reserved for observation at room temperature. The shelf-life was 1.05 years at 25℃, and 2.03 years at 20℃. |
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| Keywords: | Shelf-life Sodium phenobarbital injection |
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