Protein-bound lipids in human low density lipoproteins

In vitro oxidation of low density lipoproteins is found to be accompanied by accumulation of sterol and phospholipid residues covalently bound with apolipoprotein B. The content of protein-bound lipids in the subfraction of desialylated low density lipoproteins from healthy subjects and patients with coronary atherosclerosis is shown to be higher than that in native lipoproteins. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No. 8, pp. 155–157, August, 1995 Presented by E. I. Chazov, Member of the Russian Academy of Medical Sciences