| 老年原发性高血压患者动态脉压与高敏C-反应蛋白相关性 |
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| 引用本文： | 任军梅,王瑞英,黄淑田. 老年原发性高血压患者动态脉压与高敏C-反应蛋白相关性[J]. 中国心血管杂志, 2006, 11(1): 28-31 |
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| 作者姓名： | 任军梅 王瑞英 黄淑田 |
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| 作者单位： | 1. 山西晋城煤业集团总医院心内科,山西,晋城,048006
2. 山西医科大学第二医院心内科,山西,太原,030001 |
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| 基金项目： | 山西省教育委员会科技项目(编号200104) |
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| 摘 要： | 目的探讨老年原发性高血压(EH)患者脉压(PP)与血清高敏C-反应蛋白(hsCRP)浓度的相关性。方法435例EH老年患者体检,检测血清hsCRP及其他生化指标,比较不同PP、收缩压水平组间血清hsCRP浓度。结果EH患者PP和hsCRP之间存在明显相关性,在对高血压的其它危险因素进行调整后,这种相关性仍然存在。结论老年EH患者PP升高和hsCRP升高密切相关。炎症反应可能参与了EH的发生与发展。
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| 关 键 词： | 高血压 动态脉压 高敏C-反应蛋白 炎症 |
| 文章编号： | 1007-5410(2006)01-0028-04 |
| 收稿时间： | 2005-06-29 |
| 修稿时间： | 2005-08-09 |
Association between pulse pressure and C-reactive protein in old patient with essension hypertension |
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| REN Jun-mei,WANG Rui-ying,HUANG Shu-tian. Association between pulse pressure and C-reactive protein in old patient with essension hypertension[J]. Chinese Journal of Cardiovascular Medicine, 2006, 11(1): 28-31 |
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| Authors: | REN Jun-mei WANG Rui-ying HUANG Shu-tian |
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| Affiliation: | 1. Cardiovarscular Department, General Hospital of Shanxi Jincheng Anthracite Coal Company, Jincheng 048006, China ; 2. Cardiovarscular Department, Second Hospital of Shanxi Medical University, Taiyuan 030001, China |
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| Abstract: | Objective To investigate the relationship between circulating levels of high-sensitivity C-reactive protein(hsCRP) and pulse pressure(PP).Methods A total of 435 old subjects were sampled from out-patients and in-patients.The concentrations of high-sensitivity C-reactivite protein and serum triglycerides,LDL-C cholesterol,HDL-C cholesterol,glucose were measured.Results A positive relation was found between PP and hsCRP(P<0.001),Hcy(P<0.001).This relation remained after adjustment for classical EH risk factors.Conclusion PP elevation is associated with elevated hsCRP and Hcy levels in old patients with EH.Inflammation response might play an important role in the pathogenesis of essential hypertension. |
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| Keywords: | Essension Hypertension Ambulatory Pulse Pressure High-sensitivity C-reactive protein Inflammation |
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