| 分泌性中耳炎患者血清,中耳积液补体和免疫复合物含量测定 |
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| 引用本文： | 孙炜 刘忠强. 分泌性中耳炎患者血清,中耳积液补体和免疫复合物含量测定[J]. 临床耳鼻咽喉头颈外科杂志, 1997, 11(2): 59-60 |
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| 作者姓名： | 孙炜 刘忠强 |
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| 作者单位： | [1]青岛医学院附属医院耳鼻咽喉科 [2]青岛医学院附属医院神经病学研究室 |
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| 摘 要： | ２０例（２０耳）分泌性中耳炎患者血清与对照组血清比较，Ｃ５、Ｃ１－ＩＮＨ含量明显增高，Ｃ９、Ｂ因子（Ｂｆ）含量明显降低，免疫复合物（ＩＣ）含量明显升高。患者的中耳积液与血清比较，Ｃ３、Ｃ４、Ｃ５含量明显降低，Ｂｆ含量明显增高，ＩＣ含量明显增高，提示补体对ＩＣ清除等功能降低，有可能引起ＩＣ沉积在中耳粘膜，从而导致毛细血管通透性增加，出现中耳积液。
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| 关 键 词： | 分泌性 中耳炎 免疫测定 补体 免疫复合物 |
Determination of complements in serum and middle ear effusion of the patients with secretory otitis media |
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| Sun Wei, Liu Zhongqiang, Sun Yan et al. Determination of complements in serum and middle ear effusion of the patients with secretory otitis media[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 1997, 11(2): 59-60 |
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| Authors: | Sun Wei Liu Zhongqiang Sun Yan et al |
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| Abstract: | Complements in serum and middle ear effusion were determined in 20 patients with secretory otitis media,and compared with those in the normal controls. The C5 and C1 INH in serum of the patients were significantly higher. On the contrary,C, and B factor (Bf) were significantly lower,and the circulatory immunocomplex was also higher. In patients with secretory otitis media,the middle ear effusion levels of C3,C4 and C5 were significantly lower,and Bf and immunocomplex were significantly higher than those in serum. The results suggest that the ability of complements in clearing immunocomplex is low. Therefore,the immunocomplex may deposit in the mucosa of the middle ear. Thus the permeability of capillary will be increased,and the middle ear effusion occurs. |
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| Keywords: | Secretory otitis media Complements Immunocomplex |
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