| 星点设计-效应面法优化白芍提取工艺 |
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| 引用本文： | 何凤兰. 星点设计-效应面法优化白芍提取工艺[J]. 海峡药学, 2014, 0(8): 23-25 |
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| 作者姓名： | 何凤兰 |
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| 作者单位： | 何凤兰 (广东省佛山市中医院三水医院佛山528100)； |
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| 摘 要： | 目的优化白芍的提取工艺。方法采用星点设计-效应面法,以芍药苷提取率为考察指标对白芍提取工艺进行优化。结果优选的最佳提取工艺为加12倍量56.03%乙醇提取2次,每次45.85min。结论优选的提取工艺合理、稳定、可行。
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| 关 键 词： | 白芍 芍药苷 星点设计-效应面法 提取工艺 |
Optimization of Extraction Technology for Paeoniae Radix Alba by Central Composite Design-response Surface Methodology |
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| HE Feng-lan. Optimization of Extraction Technology for Paeoniae Radix Alba by Central Composite Design-response Surface Methodology[J]. Strait Pharmaceutical Journal, 2014, 0(8): 23-25 |
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| Authors: | HE Feng-lan |
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| Affiliation: | HE Feng-lan(Sanshui hospital Foshan City Hospital of traditional Chinese Medicine, Foshan 528100, China) |
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| Abstract: | OBJECTIVE To optimize extracting technology of Paeoniae Radix Alba. METHODS Taking extraction rate of paeoniflorin as index,extraction process of Paeoniae Radix Alba was optimized by central composite design-response surface methodology. RESULT Optimum condition of extraction technology was extracted 2 times with 12-fold,the amount of 56. 03% ethanol for 45. 85 minutes each time. CONCLUSION Optimum extraction process was reasonable,stable and feasible. |
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| Keywords: | Paeoniae Radix Alba Paeoniflorin Central composite design-response surface methodology Extraction technology |
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