河北地区电力行业6327名员工甲状腺结节危险因素Logistic回归分析

目的：分析河北地区电力行业健康体检人群甲状腺结节患病风险因素，为甲状腺疾病的防治提供科学依据。方法选择2011年1-12在我院健康管理中心行健康体检的6327名电力行业员工，均行甲状腺彩色超声检查，及血压、体重指数、腰臀比、血糖、血脂、血尿酸检测。使用二分类 Logistic回归过程对12个可疑因素与甲状腺结节发生的关系进行多因素分析。模型的拟合优度检测采用 Hosmer-Lemeshow检验。结果6327名健康体检人群甲状腺结节总检出率为39.78%，男女检出率分别为37.11%和48.60%。男性患病风险明显低于女性；随年龄增长患甲状腺结节风险增加；12个可疑因素中年龄、性别、空腹血糖与体重指数是甲状腺结节的危险因素。结论甲状腺结节在电力行业员工多发，应予重视，应积极采取相关措施，减少危险因素以避免该病发生。

Logistic Regression Analysis of Risk Factors of Thyroid Nodules in 6327 Employees of Electric Power Industry in Hebei

Objective To analyze the risk factors of thyroid nodules in healthy people taking medical examina-tions in the electric power industry in Hebei in order to provide a scientific basis for the prevention and control of thyroid disease. Methods A total of 6327 employees of the electric power industry from January to December 2011 underwent medical examinations such as examinations of color thyroid ultrasound,blood pressure,body mass index（ BMI）,waist hip ratio,blood glucose,blood lipids,blood uric acid. The relationships between 12 suspected factors and incidence of thyroid nodules were given multiplicity using binary Logistic regression,and goodness of fittest was detected using Hosmer- Lemeshow test. Results The total detection rate was 39. 78%,and male and female detection rates were 37. 11% and 48. 60% respectively. Incidence rate of male was significantly lower than that of female;the incidence rate increased with age;risk factors of thyroid nodule in the 12 suspected factors were age,gender,FBG（ fasting blood-glucose）and BMI. Conclusion Thyroid nodule has become a frequently encountered disease in employees in the electric power industry. Appropriate measures should be taken actively to reduce risk factors and avoid incidence of the disease.