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Multidrug-resistant tuberculosis detection, Latvia |
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| Authors: | Skenders Girts Fry Alicia M Prokopovica Inga Greckoseja Silvija Broka Lonija Metchock Beverly Holtz Timothy H Wells Charles D Leimane Vaira |
| Institution: | State Centre of Tuberculosis and Lung Diseases, Riga, Latvia. |
| Abstract: | To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory in Latvia, a country with epidemic MDR-TB. The assay detected rifampin resistance with 91% sensitivity and 96% specificity within 1 to 5 days (vs. 12-47 days for BACTEC). |
| Keywords: | TB/HIV control developing countries multidrug-resistant TB tuberculosis TB diagnosis dispatch |
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