Effect of Chinese Herbs for Activating Blood Circulation,Removing Stasis and Supplementing Qi on the Circulating Endothelial Cells in Patients with Unstable Angina Pectoris |
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作者姓名: | Ma Li-hong Ruan Ying-mao Jiao Zeng-mian Li Xiao-hui |
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作者单位: | Fuwai Hospital of Cardio-vascular Diseases,Union Medical University,Chinese Academy of Medical Sciences,Beijing (100037),Fuwai Hospital of Cardio-vascular Diseases,Union Medical University,Chinese Academy of Medical Sciences,Beijing (100037),Fuwai Hospital of Cardio-vascular Diseases,Union Medical University,Chinese Academy of Medical Sciences,Beijing (100037),Fuwai Hospital of Cardio-vascular Diseases,Union Medical University,Chinese Academy of Medical Sciences,Beijing (100037) |
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摘 要: | Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi (CH) on CHD-UAP patient's CEC. Methods: Sixty patients with diagnosis of CHD-UAP confirmed and differentiated to be Qi-deficiency and blood stasis by TCM were randomly divided into two groups and treated, on the basis of Western drug-therapy, with Tongxinluo capsule (通心络胶囊, TXL) and Huoxue Tongmai capsule (活血通脉胶囊, HXTM) respectively by way of oral taking three times a day, 3 capsules every time, with 1 month as one therapeutic course. The number of CEC in patients' blood circulation was counted before and after treatment. Besides, the number of CEC in 30 healthy persons was also counted for control. Results: The number of CEC in CHD-UAP patients was significantly higher than that in the he
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收稿时间: | 15 August 2004 |
Effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi on the circulating endothelial cells in patients with unstable angina pectoris |
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Authors: | Ma Li-hong Ruan Ying-mao Jiao Zeng-mian and Li Xiao-hui |
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Abstract: | Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi (CH) on CHD-UAP patient's CEC. Methods: Sixty patients with diagnosis of CHD-UAP confirmed and differentiated to be Qi-deficiency and blood stasis by TCM were randomly divided into two groups and treatime, with 1 month as one therapeutic course. The number of CEC in patients' blood circulation was counted before and after treatment. Besides, the number of CEC in 30 healthy persons was also counted for control.Results: The number of CEC in CHD-UAP patients was significantly higher than that in the healthy persons (P<0.01). After the patients were treated with CH, either TXL or HXTM, it significantly decreased (P<0.01)with insignificant difference between the two treated groups. Conclusion: CEC in CHD-UAP patients is severely damaged and endothelial function in disorder, Chinese herbs have protective effect on patients' CEC. |
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Keywords: | unstable angina pectoris endothelial cell activating blood circulation removing stasis and supplementing Qi |
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