血管内超声评价老年冠心病患者冠状动脉钙化病变的性别差异

目的应用血管内超声评价不同性别老年冠心病患者冠状动脉粥样硬化斑块钙化情况。方法选择年龄≥65岁稳定性心绞痛患者61例。所有患者均行冠状动脉造影,选取一处狭窄50%～70%的斑块进行血管内超声检查,测量血管、管腔、斑块体积及斑块钙化的弧面积。结果女性患者血管体积和管腔体积较男性明显缩小,斑块钙化弧面积明显增加(P<0.05)。结论在斑块体积相同条件下,女性患者冠状动脉粥样硬化斑块部位血管体积和管腔体积小于男性,女性患者斑块钙化负荷明显高于男性。

Gender differences of atherosclerotic plaque characteristics in elderly patients with stable angina pectoris

Objective To evaluate the gender differences of atherosclerotic plaque characteristics in elderly patients with stabel angina pectoris using intravascular ultrasound(IVUS).Methods Sixty -one elderly patients with stable angina pectoris,age≥65 years,male 33,female 28.One 50%—70%stenosis plaque was selected as target plaque in each patient.Coronary artery angiography and target plaque IVUS were performed to compare the vascular volume,lumen volume,plaque volume and calcification burden with arc area(AA).Results The vascular volume,lumen volume in female elderly patients were less than in male elderly patients(P<0.05),there were no differences in plaque volume between male and female.AA in female patients was more than in male pa-tients (P<0.05).Conclusion Female elderly patients with stable angina pectoris has smaller coronary artery and lumen at plaque segment as plaque burden was not different.Calcification burden in the plaque is more in female than in male patients.