A case with synchronous multiple liver metastases from gastric carcinoma: postoperative long-term disease-free survival |
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Authors: | Masaya Munekage Takehiro Okabayashi Norihiro Hokimoto Takeki Sugimoto Hiromichi Maeda Tsutomu Namikawa Ken Dabanaka Michiya Kobayashi Keijiro Araki and Kazuhiro Hanazaki |
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Institution: | (1) Department of Surgery, Kochi Medical School, Kohasu-Okocho, Nankoku-City Kochi, 783-8505, Japan |
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Abstract: | Purpose We herein report a case with synchronous multiple liver metastases from gastric carcinoma surviving disease-free for more
than 10 years after hepatic resection.
Methods A 64-year-old male admitted to our hospital because of constitutional wariness. Preoperative diagnosis was type 1 gastric
cancer at the lower third of the stomach and multiple metastases of both hepatic lobes. After we performed distal gastrectomy
with regional lymphadenectomy and wedge hepatic resection for eight metastatic liver tumors, he received 5-fluoropyrimidine
and platinum-based adjuvant chemotherapy during the early postoperative period.
Results The pathologic examination revealed moderately differentiated gastric adenocarcinoma with regional lymph node metastasis and
multiple liver metastases. The postoperative course was uneventful and the patient is doing well without disease recurrence
after more than 10 years following surgery.
Conclusion To the best of our knowledge, this patient is the longest disease-free survivor after liver resection for synchronous multiple
liver metastases from advanced gastric cancer. In this modern era of developing liver surgery and adjuvant chemotherapy, combination
therapy of aggressive surgery and early postoperative adjuvant chemotherapy for advanced gastric cancer with liver metastasis
may allow long-term survival in selected patients. |
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Keywords: | Gastric cancer Liver metastasis Surgery Gastrectomy Hepatectomy |
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