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血清透明质酸测定及其临床意义
引用本文:盛珏,陆玮,徐培康.血清透明质酸测定及其临床意义[J].复旦学报(医学版),1992(4).
作者姓名:盛珏  陆玮  徐培康
作者单位:上海医科大学华山医院内科 (盛珏,陆玮),上海市放射医学研究所(徐培康)
摘    要:用放射免疫法测定20例正常人和108例各类肝病患者的血清透明质酸(HA)含量,并与血清前胶原肽(PIIIP)组比较。结果表明:血清HA较灵敏地随肝病的演变而变化,随病程发展升高幅度不相同,有助于对慢性迁延性肝炎、慢性活动性肝炎的诊断及鉴别诊断,在反映肝损害、预示肝硬化上比PIIIP灵敏。

关 键 词:透明质酸  慢性迁延性肝炎  慢性活动性肝炎  肝硬化

DETERMINATION OF SERUM HYALURONIC ACID AND ITS CLINICAL SIGNIFICANCE
Sheng Jue,Lu Wei,Xu Peikang.DETERMINATION OF SERUM HYALURONIC ACID AND ITS CLINICAL SIGNIFICANCE[J].Fudan University Journal of Medical Sciences,1992(4).
Authors:Sheng Jue  Lu Wei  Xu Peikang
Abstract:Using radioimmunoassay method, serum hyaluronic aoid (HA) was determined serially in 20 healthy subjects and 108 patients with liver diseases. Comparison was made between the serum HA levels and the ooncomitantly determined serum prooollagen type III aminoterminal polypeptide (PIIIP} levels. The results showed that the serum HA is increased during the progression of the diseases, and is more sensitive than serum PIIIP in detecting the activity of the diseases. Serum HA determination is useful in the diagnosis and differential diagnosis of chronic persistent hepatitis and chronic active hepatitis.
Keywords:hyaluronic aeid  chronic persistent hepatitis  ohronic active hepatitis  hepatitis cirrhosis  
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