| 4,6-苄叉基-D-葡萄糖抗癌作用的研究 |
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| 引用本文： | 张宝凤,牟孝硕,肖功政,王玉珠,韩丽梅. 4,6-苄叉基-D-葡萄糖抗癌作用的研究[J]. 沈阳药科大学学报, 1990, 0(3) |
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| 作者姓名： | 张宝凤 牟孝硕 肖功政 王玉珠 韩丽梅 |
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| 作者单位： | 沈阳药学院药理教研室，沈阳药学院药理教研室，沈阳药学院药理教研室，沈阳药学院药化教研室，沈阳药学院药化教研室 51期学生 |
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| 摘 要： | 本文证明,4、6-苄叉基-D-葡萄糖(BG)i·p,50、100mg/kg对Walker 256和62.5、125mg/kg对EAC实体型移植性肿瘤均有明显抑制作用,对HepA实体型和EAC腹水型则无抑癌活性。体外实验表明,BG 100μg/ml对Hela细胞无活性,200μg/ml对EAC细胞有一定抑制作用。BG i.v LD_(50)为200mg/kg以上。i.p 350mg/kg以上。
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| 关 键 词： | 4,6-苄叉基-D-葡萄糖 EAC HepA Walker 256 Hela 抗肿瘤作用 |
ANTITUMOR ACTIVITY OF 4,6-BENZYLIDENE-D-GLUCOSE(BG)ON EXPERIMENTAL TUMOR |
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| Zhang Baofeng. ANTITUMOR ACTIVITY OF 4,6-BENZYLIDENE-D-GLUCOSE(BG)ON EXPERIMENTAL TUMOR[J]. Journal of Shenyang Pharmaceutical University, 1990, 0(3) |
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| Authors: | Zhang Baofeng |
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| Affiliation: | Zhang Baofeng,Department of Pharmacology |
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| Abstract: | In this study we demonstrated that BG had obvious antitumor effect on Wal-ker 256 in rats and on EAC(solid) in mice. But BG showed no significant activityagainst HepA(solid) and EAC(ascites), In vitro test showed that BG inhibited thegrowth of HELA cells at the concentration of 200μg/ml. |
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| Keywords: | 4 6-Benzylidene-D-glucose EAC HepA Walker 256 Hela Antitumor |
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