| 吴茱萸碱对人胃腺癌细胞SGC-7901作用的研究 |
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| 引用本文： | 田秀丽,张瑾,王小亮,王珊,史祺云,赵广厚,全龙泉,宋宇. 吴茱萸碱对人胃腺癌细胞SGC-7901作用的研究[J]. 北京中医药大学学报, 2011, 34(2): 115-118 |
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| 作者姓名： | 田秀丽 张瑾 王小亮 王珊 史祺云 赵广厚 全龙泉 宋宇 |
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| 作者单位： | 吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062;吉林大学畜牧兽医学院,吉林,130062 |
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| 基金项目： | 教育部博士科学点专项科研基金资助项目(No.20070183158); 吉林省教育厅科研计划资助项目(No.吉教科合字[2005]第55号) |
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| 摘 要： | 目的 研究吴茱萸碱(Evo)对人胃腺癌(SGC-7901)细胞的作用,并初步探讨其作用机制.方法 MTT法测定Evo的抗肿瘤活性;电镜观察Evo对细胞形态学的影响;琼脂糖凝胶电泳检测Evo对细胞DNA电泳行为的影响;流式细胞技术检测Evo对SGC-7901细胞的抑制作用和细胞周期的影响.结果 一定浓度范围内Evo对SG...
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| 关 键 词： | 吴茱萸碱 人胃腺癌细胞 抗肿瘤 凋亡 周期阻滞 |
Effect of evodiamine on human gastric adenocarcinoma cell line(SGC-7901) |
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| TIAN Xiu-li,ZHANG Jin,WANG Xiao-liang,WANG Shan,SHI Qi-yun,ZHAO Guang-hou,QUAN Long-quan,SONG Yu. Effect of evodiamine on human gastric adenocarcinoma cell line(SGC-7901)[J]. Journal of Beijing University of Traditional Chinese Medicine, 2011, 34(2): 115-118 |
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| Authors: | TIAN Xiu-li ZHANG Jin WANG Xiao-liang WANG Shan SHI Qi-yun ZHAO Guang-hou QUAN Long-quan SONG Yu |
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| Affiliation: | TIAN Xiu-li,ZHANG Jin,WANG Xiao-liang,WANG Shan,SHI Qi-yun,ZHAO Guang-hou,QUAN Long-quan,SONG Yu(College of Animal Husbandry and Veterinary Medicine,Jilin University,Jilin 130062) |
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| Abstract: | Objective To study the effect of evodiamine(Evo) on human gastric adenocarcinoma cell line(SGC-7901) and discuss the mechanism.Methods The anti-tumor activity of Evo was determined by using MTT assay,and the influence of Evo on morphological changes was observed with the transmission electron microscope(TEM).The influence of Evo on the electrophoretic behavior of DNA was detected by using agarose gel electrophoresis,and the inhibitory effect and influence of Evo on SGC-7901 and cell cycle were detected by u... |
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| Keywords: | evodiamine human gastric adenocarcinoma cell line(SGC-7901) anti-tumor apoptosis cell cycle arrest |
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