| 益精方对环磷酰胺小鼠少弱精症模型精子凋亡的干预作用 |
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| 引用本文： | 罗少波,胡海翔,贾金铭.益精方对环磷酰胺小鼠少弱精症模型精子凋亡的干预作用[J].北京中医药大学学报,2011,34(2):119-121,130. |
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| 作者姓名： | 罗少波 胡海翔 贾金铭 |
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| 作者单位： | 空军总医院男科中心,北京,100142;中国中医科学院广安门医院男科 |
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| 摘 要： | 目的 探讨补肾益精、补血活血中药方剂益精方对环磷酰胺小鼠少弱精模型精子凋亡的影响.方法 将40只雄性昆明小鼠随机分为对照组、模型组、小剂量治疗组和大剂量治疗组.按60 mg/kg给对照组小鼠腹腔注射生理盐水,60 mg/kg给模型组、小剂量治疗组、大剂量治疗组小鼠腹腔注射环磷酰胺,每天1次,连续5 d.第6天开始按体重...
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| 关 键 词： | 精子 凋亡 益精方 小鼠 |
Intervention effect of Yijing Formula on sperm apoptosis in mouse model of oligoasthenospermia induced by CTX |
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| LUO Shao-bo,HU Hai-xiang,JIA Jin-ming.Intervention effect of Yijing Formula on sperm apoptosis in mouse model of oligoasthenospermia induced by CTX[J].Journal of Beijing University of Traditional Chinese Medicine,2011,34(2):119-121,130. |
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| Authors: | LUO Shao-bo HU Hai-xiang JIA Jin-ming |
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| Institution: | LUO Shao-bo1,HU Hai-xiang1,JIA Jin-ming2(1 Center of Andrology,General Hospital of Air Force,Beijing 100142,2 Department of Andrology,Guang'anmen Hospital,China Academy of Chinese Medical Scienes) |
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| Abstract: | Objective To investigate the influence of Yijing Formula(with the actions of tonifying kidney and replenishing essence,and tonifying and activating blood) on sperm apoptosis in mouse model of oligoasthenospermia(OAT) induced by cyclophosphamide(CTX).Methods Male Kunming mice(n=40) were randomly divided into the control group(CG),model group(MG),small-dose treatment group(SG) and large-dose treatment group(LG).CG was given intraperitoneal injection of normal saline solution(60 mg/kg) once a day for 5 days,an... |
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| Keywords: | sperm apoptosis Yijing formula mice |
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