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远位功能化及其在甾体药物合成中的应用
引用本文:夏鹏,郑筠青. 远位功能化及其在甾体药物合成中的应用[J]. 中国医药工业杂志, 1987, 0(6)
作者姓名:夏鹏  郑筠青
作者单位:上海医科大学药学系,上海第十二制药厂
摘    要:
本文综述了新近发展起来的远位功能化技术的原理及其在甾体药物合成中的应用,包括通过9-位选择性氢化引入11-羟基以及甾醇17位边链的切除等。

关 键 词:远位功能化  甾体药物  合成

REMOTE FUNCTIONALIZATION AND ITS APPLICATION IN SYNTHESIS OF STEROID DRUGS
XIA Peng. REMOTE FUNCTIONALIZATION AND ITS APPLICATION IN SYNTHESIS OF STEROID DRUGS[J]. , 1987, 0(6)
Authors:XIA Peng
Affiliation:XIA Peng (Shanghai Medical Univercity)ZHENG Yun-qing (Shanghai 12th Pharmaceutical Factory)
Abstract:
The principle and application of recently developed remote func-tionalization in synthesis of steroid drugs are reviewed,including the introduc-tion of 11-hydroxy group via selective chlorination at 9-position and the cleavageof 17-side chain of sterols,etc.
Keywords:remote functionalization  steroid drugs  synthesis
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