| 树突状细胞疫苗治疗脑胶质瘤进展 |
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| 引用本文： | 徐昊,王占祥.树突状细胞疫苗治疗脑胶质瘤进展[J].国际肿瘤学杂志,2011,38(8):596-598. |
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| 作者姓名： | 徐昊 王占祥 |
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| 作者单位： | 361000,厦门大学附属第一医院神经外科 |
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| 摘 要： | 树突状细胞(DC)介导的肿瘤疫苗应用于脑胶质瘤治疗，通过选择更合适的靶点，增强了DC疫苗的特异性。由基因工程转入抗细胞凋亡蛋白，获得了寿命更长、效能更高的DC疫苗。随着临床经验的积累，DC疫苗的疗效得到了显著提高。
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| 关 键 词： | 树突细胞 神经胶质瘤 癌症疫苗 免疫疗法 |
| 收稿时间： | 2011-03-15; |
| 修稿时间： | 2011-07-12 |
Dendritic cell vaccines in glioma treatment |
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| XU Hao,WANG Zhan-xiang.Dendritic cell vaccines in glioma treatment[J].Journal of International Oncology,2011,38(8):596-598. |
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| Authors: | XU Hao WANG Zhan-xiang |
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| Abstract: | Dendritic cell ( DC)-based tumor vaccine is applied to the gliomas treatment. Target selection heightens the specificity of DC vaccine, while obtaining of highly immunogenic long-lived and more effective DC vaccines by genetic engineering to antiapoptotic protein gene transfer. With the accumulation of clinical experience, the clinical curative effect of DC vaccine has been materially improved. |
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| Keywords: | Dendritic cells Glioma Cancer vaccines Immunotherapy |
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