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骨髓纤维化转化为急性淋巴细胞白血病1例报道并文献复习
引用本文:郑兵荣,范翠华,杨阳,胥昀,傅丽娟. 骨髓纤维化转化为急性淋巴细胞白血病1例报道并文献复习[J]. 浙江中医药大学学报, 2012, 36(7): 787-788
作者姓名:郑兵荣  范翠华  杨阳  胥昀  傅丽娟
作者单位:浙江中医药大学附属第二医院,杭州310005
摘    要:[目的]通过骨髓纤维化(myelofibrosis,MF)转化为急性淋巴细胞白血病(简称急淋)1例报道,结合文献分析,探讨MF的转归及预后。[方法]对2011年7月就诊于浙江中医药大学第二附属医院血液科的1例MF转化为急淋的患者的诊治过程进行报道,并检索文献复习分析。[结果]MF患者转化为急淋极为罕见,且预后极差,本例患者通过中西医结合治疗,取得一定疗效。[结论]MF患者有5%~20%的机会转化成急性白血病,转化为急性淋巴细胞白血病极为罕见,且预后极差,中西医结合治疗具有一定疗效,但总体预后仍欠佳。

关 键 词:MF  急性淋巴细胞白血病  病例报道

Reportand Documentary Reyiew on Myelonbrosis Transferring to Acute Lymphocyte Leukaemia
Affiliation:Zheng Binrong, Fan Cuihua, Yang Yang, etal Second Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou(310005)
Abstract:[Objective] To explore the lapse and prognosis of myelofibrosis by combing documentary analysis and report on myelofi- brosis transferring to acute lymphocyte leukaemia. [Method] Make a report on the diagnosis and treatment to one case of myelofibrosis transferring to acute lymphocyte leukaemia, and retrieve documents for analysis. [Result] Such disease is very rare with bad prognosis; with treatment of combining TCM and WM, it got good cure effect. [Conclusion] Myelofibrosis has 5-20% of op- portunity for acute lymphocyte leukaemia. Combination of TCM and WM has definite advantages in such disease, but without very good prognosis.
Keywords:myelofibrosis  acute lymphocyte leukemia  case report
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