小梁切除术联合甲钴胺治疗晚期青光眼的疗效观察

目的：探讨小梁切除术联合甲钴胺治疗晚期青光眼的疗效。方法：选择46例晚期青光眼行小梁切除术,术中应用可拆除调整缝线,术后联合应用口服甲钴胺糖衣片0.5g tid,连续3~6个月。结果：术前眼压平均值为38.97＋2.91mmHg,术后眼压平均值为14.41＋2.17 mmHg。术后2周视力提高大于两行10眼（21.74%）,视力提高小于两行20眼（43.48%）,不提高14眼（30.43%）,减退2眼（4.34%）,追踪观察6~24个月,无视力丧失。视野改善8眼（17.39%）,视野不变34眼（73.91%）,视野缩窄4眼（8.70%）。结论：晚期青光眼通过小梁切除术,联合视神经保护剂的应用,可有效控制眼压,避免视力过早丧失。

CLINICAL EFFECTS OF TRABECULECTOMY COMBINED WITH MECOBALAMIN IN TREATING LATE GLAUCOMA

Objective：To investigate the effects of trabeculectomy combined with mecobalamon in treating late glaucoma.Methods：46 patients with late glaucoma were treated by trabeculectomy.Adjustable suture was applied.All patients received mecobalamin therapy after operation for 3 to 6 months.Results：Mean intraocular pressure（IOP） before and after operation was 38.97±2.91mmHg,and 14.41±2.17mmHg.In terms of vision change 2 weeks after operation： 10 eyes（21.74%） improved by more than two lines,20 eyes（43.48%） improved by less than two lines,14 eyes（30.43%） showed no improvement,and 2 eyes（4.34%） decreased.All 46 patients were followed-up for 6 to 24 monthes,no loss of vision ever found.In terms of visual field after operation：8 eyes（17.39%） improved,34 eyes（73.91%） had no change,and 4 eyes（8.70%） worsened.Conclusion：For late glaucoma,trabeculectormy combined with neuroprotective agents can effectively control IOP and slow down the loss of visual function.