Action of apilak on the electrolyte and catecholamine content of the wall of arterial vessels at different levels of systemic arterial pressure

In cats with elevated systemic arterial blood pressure apilac (1 mg/kg, a single dose or course administration) significantly decreased the arterial vessel wall contents of ions of Na+, Ca2+ and catecholamines the levels of which exceeded control values. Apilac administration to animals with normal systemic arterial blood pressure resulted in a decrease of Ca2+ ion content, an increase of Na+, K+ and Mg2+ ion concentrations in the vessel wall. The content of catecholamines remained in the range of control values.