棕榈花蕾水提物抗雌性小鼠生育作用 |
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引用本文: | 齐汝霞,张鹏,姚晓红,王传功,李卫平. 棕榈花蕾水提物抗雌性小鼠生育作用[J]. 济宁医学院学报, 2013, 0(4): 253-255 |
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作者姓名: | 齐汝霞 张鹏 姚晓红 王传功 李卫平 |
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作者单位: | [1]安徽医科大学基础学院,安徽合肥230032 [2]济宁医学院基础学院,山东济宁272067 [3]济宁医学院附属济宁市第一人民医院,济宁272011 |
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摘 要: | 目的 探讨棕榈花蕾水提物对雌性小鼠的抗着床、抗早孕及避孕作用.方法 给雌性小鼠分别用低剂量(2.5g/kg) 、中剂量(5g/kg)和高剂量(10g/kg)的棕榈花蕾水提物灌胃,研究其抗着床、抗早孕及避孕作用.结果 抗着床实验中低、中、高剂量棕榈花蕾水提物对小鼠的妊娠抑制率为60% 以上,中高剂量棕榈花蕾水提物对早期妊娠小鼠有明显致流产作用.中、高剂量棕榈花蕾水提物能使小鼠的避孕率达100%.结论 棕榈花蕾水提物具有显著的抗着床、抗早孕及避孕作用.
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关 键 词: | 棕榈花蕾水提物 雌性小鼠 抗着床 抗早孕 避孕 |
The effect of aqueous extract of kittul alabastrum on antifertility in female mice |
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Affiliation: | QI Ru-xia , ZHANG Peng ,YAO Xiao-hong , et a l (Academy of Basic Medicine,Anhui Medical University, Hefei 230032, China) |
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Abstract: | Objective To explore anti-implantation, anti-early pregnancy function and contraceptive effect of aqueous extract of kittul alabastrum in mice. Methods To study the effect of anti-implantation, anti-early pregnancy function and contraceptive effect of mice which were given aqueous extract of kittul alabastrum with 2.5 g/ kg, 5 g/kg, 10g/kg. Results In the experiment of anti-implantation, inhibition rate of pregnancy was over 60 %, and middle and high dose group induced miscarriage of early pregnancy mice. Contraception rate of middle dose and high dose group was 100%. Conclusion Aqueous extract of kittul alabastrum was anti-implantation, anti-early pregnancy and contraceptive effect on female mice. |
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Keywords: | Aqueous extract of kittul alabastrum Mice Anti-implantation Anti-early pregnancy Contraceptive effect |
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