Higher cerebral dysfunction in a case with atypical multiple sclerosis with concentric lesions |
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Authors: | CHIKAKO MORIOKA KEN NAMETA YOICHI KOMATSU TAKEHIKO TSUTIO HIDEKI KONDO |
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Institution: | Department of Neuropsychiatry, Osaka Rosai Hospital;Department of Neuropsychiatry, Osaka Teishiti Hospital, Osaka, Japan |
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Abstract: | Abstract A patient with atypical multiple sclerosis (MS) with clear concentric structure was studied using high field magnetic resonance imaging (MRI). This case was considered to be Balo's concentric sclerosis. Magnetic resonance imaging showed diffuse multiple concentric demyelinating lesions in the bilateral centrum semiovales, which finally regressed with the necrotic lesions remaining when the patient was discharged. During his clinical course, he showed some higher cerebral dysfunctions, such as memory disturbance, constructual apraxia and acalculia. He was treated with glycerin, prednisone and rehabilitation; all of which were effective in his recovery. Over a 4 month period, the patient recoveredclinically, but some intellectual impairment remained. |
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Keywords: | apraxia Balo's concentric sclerosis higher cerebral dysfunction magnetic resonance imaging multiple sclerosis neuropsychological findings |
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