等离子体活化羟基磷灰石(HA)的机理研究

用等离子体活化改性HA,并用模拟体液中类骨磷灰石的形成和扫描电镜、光电子能谱、X射线衍射等对其进行了表征。结果发现与活化改性前相比较,等离子体活化改性后的HA更有利于类骨磷灰石的形成。活化机理是等离子体中丰富的高能、高活性的粒子轰击HA,使其被刻蚀和粗化,增加了HA表面的溶解性和提供了更多的活性位点,易使局域的钙、磷离子浓度达到过饱和,更有利于类骨磷灰石的成核和生长。表明等离子体改性提高了HA的生物活性。

On the Active Mechanism of Hydroxyapatite Modified by Cold Plasma

The surface modification using cold plasma technique was introduced to hydroxyapatite(HA). The methods adopted in the study included the formation of bone-like apatite in simulated body fluld and the use of SEM,XPS and XRD. The results showed that the formation of bone-like apatite on HA modified by cold plasma was easier than that without modification. The active mechanism involves the impact of the particles with high energy and high activity against HA, which roughens and etches the surface of HA, heads to the distortion of HA crystal, and thus increases the dissolvability of HA and the local concentration of the Ca and P ions. This approach is helpful to the formation of bone-like appetite. The data demonstrate that the surface modification using cold plasma technique can increase the activity of HA.