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The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics |
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| Authors: | Sugatani Junko Yamakawa Kasumi Tonda Eri Nishitani Shinichi Yoshinari Kouichi Degawa Masakuni Abe Ikuro Noguchi Hiroshi Miwa Masao |
| Institution: | Department of Pharmaco-Biochemistry and COE 21, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka 422-8526, Japan. |
| Abstract: | |
| Keywords: | AhR aryl hydrocarbon receptor AhRE AhR response element bp base pair(s) CAR constitutive androstane receptor CARE CAR response element CYP cytochrome P450 DMSO dimethyl sulfoxide DR direct repeat hAhR human AhR hCAR human CAR hPXR human PXR kb kilobase pairs PBREM phenobarbital-responsive enhancer module PCR polymerase chain reaction pGL3-tk pGL3-tk-firefly luciferase vector PXR pregnane X receptor PXRE PXR response element RXR retinoid X receptor tk thymidine kinase promoter UGT UDP-glucuronosyltransferase |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |