| 头孢曲松治疗早期梅毒的Meta分析 |
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| 引用本文： | 梁思,宋佩华. 头孢曲松治疗早期梅毒的Meta分析[J]. 中国性科学, 2013, 22(4): 52-53,60 |
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| 作者姓名： | 梁思 宋佩华 |
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| 作者单位： | 梁思 (卫生部中日友好医院皮肤科,北京,100029)； 宋佩华 (卫生部中日友好医院皮肤科,北京,100029)； |
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| 摘 要： | 目的：评价头孢曲松治疗早期梅毒的有效性和安全性.方法：根据纳入和排除标准,通过检索Cochrane图书馆、MEDLINE、EMBASE、CNKI等数据库,查找头孢曲松和普鲁卡因青霉素治疗早期梅毒的随机对照试验.试验数据采取RevMan5.2软件进行Meta分析.结果：纳入3个随机对照试验,结果显示头孢曲松在治疗早期梅毒后1年内在皮疹消退和RPR转阴方面（OR=0.40,95%CI[0.09-1.71],P=0.63）和普鲁卡因青霉素相比无明显差异.结论：头孢曲松是治疗早期梅毒的有效药物.
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| 关 键 词： | 头孢曲松 早期梅毒 随机对照试验 Meta分析 |
A Meta - analysis of ceftriaxone in the treatment of early syphilis |
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| LIANG Si,SONG Peihua. A Meta - analysis of ceftriaxone in the treatment of early syphilis[J]. The Chinese Journal of Human Sexuality, 2013, 22(4): 52-53,60 |
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| Authors: | LIANG Si SONG Peihua |
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| Affiliation: | ( Department of Dermatology, Sino -Japanese Friendship Hospital, Beijing 100029, China) |
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| Abstract: | Objectives： To evaluate the effectiveness and safety of ceftriaxone in treating early syphilis. Methods： Based on the inclusion and exclusion standards, we searched the clinical trial literatures which compared the efficacy and safety of ceftri-axone and procaine pencillin from Cochrane Library,MEDLINE,EMBASE and CNK. With these data, we used RevMan5.2 to conduct meta - analysis. Results： The results of three randomized controlled trials showed that there was no significant difference between eeftriaxone and procaine penicillin in terms of defloreseenee and RPR becoming negtive after one - year treatmem of early syphilis. （OR = 0.40,95 % C1 [0.09 to 1.71 ] ,P = 0.63 ）. Conclusion： Ceftriaxone is an effective and safe medicine for trea-ting early syphilis. |
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| Keywords: | Ceftriaxone Early syphilis Randomized controlled trials Meta - analysis |
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