长QT综合征的诊断与治疗

长QT综合征包括先天性及获得性长QT综合征。经研究，先天性长QT综合征目前已明确了13个常染色体显性遗传基因型和2个常染色体隐性遗传基因型，临床最为常见的是LQT1、LQT2和LQT3。不同基因型其临床表现、心电图表现、诱发方式不同，治疗、预后均有区别。获得性长QT综合征多因药物、代谢异常及心肌疾病诱发，目前获得性长QT综合征越来越多的受到人们的关注，部分已上市的药物因其严重心脏毒副作用而相继撤市，新药心脏安全性的规范化条例已出台实施。

Diagnosis and Treatment of Long QT Syndrome

Long QT syndrome （LQTS） includs congenital and acquired long QT syndrome. Now, acquired long QT syndrome has been established the 13 autosomal dominant genetic types and two autosomal recessive genetic types, and the most common clinical is LQT1, LQT2 and LQT3. The genotypes decide the difference of their clinical manifestations, electrocardiography, cause, treatment and prognosis. Ac- quired long QT syndrome is induced due to drugs, metabolism and myocardial disease. Now,long QT syndrome has been paid attention by more and more people, with some drugs withdrawl due to its serious side effects on the heart. The new drugs safety regulations on the heart has been implemented.