| 神经生长因子对豚鼠噪声性听力损伤的保护作用 |
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| 引用本文： | 阮芳铭,高文元,王海明,季红光,王福(),肖建平,王兰英,潘祥福,刘长云. 神经生长因子对豚鼠噪声性听力损伤的保护作用[J]. 第二军医大学学报, 2000, 21(1): 45-49 |
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| 作者姓名： | 阮芳铭 高文元 王海明 季红光 王福() 肖建平 王兰英 潘祥福 刘长云 |
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| 作者单位： | 第二军医大学海军医学第海军卫生学教研室,上海,200433 |
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| 基金项目： | 国家自然科学基金!资助项目（39870203） |
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| 摘 要： | 目的：探讨神经生长因子（ｎｅｒｖｅ ｇｒｏｗｔｈ ｆａｃｔｏｒ,ＮＧＦ）对噪声性听力损伤的保护作用。方法;以听阈,耳蜗酶组织化学检测等为指标,观察豚鼠每天在１１５ｄＢ（Ａ）稳态噪声连续６ｄ的暴露（４５ｍｉｎ／ｄ）前,肌肉注射不同剂量的ＮＧＦ及鼠皮层声诱发电位,听毛细胞琥珀酸脱氢酶（ｓｕｃｃｉｎｉｃ ｄｅｈｙｄｒｏｇｅｎａｓｅ,ＳＤＨ）活性的影响。结果：Ａ「ＮＧＦ：１００ＢＵ／（ｋｇ．ｄ）,ｉｍ．」
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| 关 键 词： | 神经生长因子 耳聋 噪音性耳聋 豚鼠 |
| 文章编号： | 0258-879X(2000)01-0045-05 |
| 修稿时间： | 1999-09-05 |
Protective effects of nerve growth factor on noise-induced hearing damage in guinea pigs |
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| RUAN Fang-Ming,GAO Wen-Yuan,WANG Hai-Ming,JI Hong-Guang,WANG Fu-Di,XIAO Jian-Ping,WANG Lang-Ying,PAN Xiang-Fu,LIU Chang-Yun. Protective effects of nerve growth factor on noise-induced hearing damage in guinea pigs[J]. Former Academic Journal of Second Military Medical University, 2000, 21(1): 45-49 |
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| Authors: | RUAN Fang-Ming GAO Wen-Yuan WANG Hai-Ming JI Hong-Guang WANG Fu-Di XIAO Jian-Ping WANG Lang-Ying PAN Xiang-Fu LIU Chang-Yun |
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| Affiliation: | RUAN Fang-Ming(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)GAO Wen-Yuan(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)WANG Hai-Ming(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)JI Hong-Guang(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)WANG Fu-Di(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)XIAO Jian-Ping(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)WANG Lang-Ying(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)PAN Xiang-Fu(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China)LIU Chang-Yun(Department of Navy Hygienie, Faculty of Navy Medicine,Second Military Medical University,Shanghai 200433, China) |
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| Abstract: | |
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| Keywords: | nerve growth factor noise auditory threshold succinic dehydrogenase |
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