| 700 kPa空气和氮氧混合气条件下大鼠脑电图的变化 |
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| 引用本文： | 杨涛,潘令松,毕钢,肖卫兵,刘景昌.700 kPa空气和氮氧混合气条件下大鼠脑电图的变化[J].海军医学杂志,2001,22(4):296-298. |
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| 作者姓名： | 杨涛 潘令松 毕钢 肖卫兵 刘景昌 |
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| 作者单位： | 杨涛（海军医学研究所,上海,200433）;潘令松（海军医学研究所,上海,200433）;毕钢（海军医学研究所,上海,200433）;肖卫兵（海军医学研究所,上海,200433）;刘景昌（海军医学研究所,上海,200433） |
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| 基金项目： | 基金项目:全军医药卫生科研基金资助项目(98M049) |
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| 摘 要： | 目的：探讨700kPa空气和氮氧混合气对大鼠脑电活动的影响。方法：将清醒大鼠分别在700kPa空气和氮氧混合气（PO2为22kPa)中暴露15min，通过头皮针电极记录其脑电图及功率谱。结果：和加压前对比，700kPa空气中，大鼠脑电频率和波幅均无显著变化；700kPa氮氧混合气中，大鼠脑电频率变慢（P＜0．05），波幅无显著变化。结论：700kPa空气对大鼠脑电影响不明显；700kPa氮氧混合气中，即氮分压达到678kPa时可对大鼠脑电活动产生较明显影响。
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| 关 键 词： | 氮麻醉 脑电图 氧氮混合 |
| 文章编号： | 1009-0754(2001)04-0296-03 |
| 修稿时间： | 2000年5月15日 |
EEG Changes in Rats under 700 kPa Air and Nitrogen-oxygen Mixture Pressure |
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| YANG Tao,PAN Ling song,BI Gang,et al.EEG Changes in Rats under 700 kPa Air and Nitrogen-oxygen Mixture Pressure[J].Journal of Navy Medicine,2001,22(4):296-298. |
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| Authors: | YANG Tao PAN Ling song BI Gang |
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| Abstract: | Objective:To explore the effects on EEG in rats of 700 kPa air and nitrogen oxygen mixture pressure. Methods: Rats were compressed to 700 kPa with compressed air and nitrogen oxygen mixture (PO 2=22 kPa) and left for 15 minutes. Spontaneous EEG was recorded. Results: No significant changes were found in rat EEG frequency and amplitude under 700 kPa air pressure before and after the compression. Under 700 kPa nitrogen oxygen mixture pressure, the rat EEG frequency decreased, and the difference was significant. There were no significant changes in EEG amplitude. Conclusion: 700 kPa air pressure had no significant effect on rat EEG activity. 700 kPa nitrogen oxygen mixture pressure reduced rat EEG frequency significantly. High partial pressure oxygen may take an antagonistic effect on nitrogen narcosis. |
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| Keywords: | nitrogen narcosis EEG |
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