脑梗死与颈动脉粥样硬化斑块的相关性研究

目的探讨脑梗死与颈动脉粥样硬化斑块的相关性。方法采用彩色多普勒血流成像技术对50例脑梗死患者进行检测,观察其梗死侧和非梗死侧颈动脉内中膜厚度、斑块的部位、大小及其数目、动脉狭窄程度以及血流动力学改变等,并与48例对照组颈动脉粥样硬化斑块检出情况进行比较。结果脑梗死组患者的颈动脉粥样硬化斑块检出率为62%,显著高于对照组(18.7%,P<0.01)。颈动脉粥样硬化斑块多发生在梗死病灶的同侧,占72%,以颈总动脉分叉处居多,占52%。斑块大小及其数量,峰值流速、搏动指数与脑梗死有明显的相关性(P<0.05),而颈动脉内中膜厚度、狭窄程度无明显差异(P>0.05)。结论脑梗死的发生与颈动脉粥样硬化斑块密切相关,防止斑块的形成对防止脑梗死的发生有非常重要的意义。

Evaluation Of the correlation between cerebral stroke and carotid atherosclerotic plaque

Objective To evaluate the correlation between the cerebral stroke and carotid atherosclerotic plaque.Methods Using the color Dopplerul trasonography technique,the carotid intimalmedial thickness,the number and position of plaques,the extent of lumen narrowing and cerebral homodynamic changes were measured at both the infarction and infarction flee sides in 50 patients with cerebral stroke,and compared with the controlled group.Results There were 62% patients showed presence of carotid arteriosclerosis plaques in 50 patients,the incidence was significant higher than those in control group(18.7%,P<0.01).Most of them occurred at the same side of stroke focus(72%),especially in the bifurcation of common carotid artery(52%).The numbers of plaques,pulsatility index and peak velocity were significantly related to the stroke(P<0.05),while there were no difference between the IMT and the extent of lumen narrowing(P>0.05).Conclusion Stroke occurrence is closely correlated to the carotid arteriosclerotic plaques,and dislodgment of plaques is the main reason of stroke.Prevention of plaques formation has important significance to avoid stroke events.