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Lignan glycosides and flavonoids from Saraca asoca with antioxidant activity
Authors:Samir Kumar Sadhu  Amina Khatun  Panadda Phattanawasin  Takashi Ohtsuki  Masami Ishibashi
Affiliation:(1) Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan;(2) Pharmacy Discipline, Life Science School, Khulna University, Khulna, 9208, Bangladesh;(3) Faculty of Pharmacy, Silpakorn University, Nakorn Pathom, 73000, Thailand
Abstract:Five lignan glycosides, lyoniside, nudiposide, 5-methoxy-9-β-xylopyranosyl-(−)-isolariciresinol, icariside E3, and schizandriside, and three flavonoids, (−)-epicatechin, epiafzelechin-(4β→8)-epicatechin and procyanidin B2, together with β-sitosterol glucoside, were isolated from a methyl alcohol (MeOH) extract of Saraca asoca dried bark. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) and mass spectroscopic analysis. Antioxidant activities were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay.
Keywords:Saraca asoca   Caesalpiniaceae  Lignan glycoside  Flavonoid  Antioxidant activity
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