电针对家兔视前区-下丘脑前部温度感受神经元放电的影响

<正> 针刺可以降低体温已经动物实验和临床实践证明,但其作用机理尚未完全清楚,特别是对体温调节中枢的作用报道甚少。本工作以家兔视前区-下丘脑前部(PO-AH)温度感受神经元自发放电为指标,观察电针对其放电活动的影响,探讨针刺对体温调节中枢的调整作用。方法家兔18只,雌雄不拘,体重1.7～2.3公斤,以氨基甲酸乙酯(1克/公斤)静脉麻醉。手术包括气管插管,小脑延髓池引流和开颅。手术后,兔头固定于立体定向仪上,

THE EFFECT OF THE ELECTRO-ACUPUNCTURE ON THE UNIT DISCHARGE OF THERMOSENSITIVE NEURONS IN THE PREOPTIC--ANTERIOR HYPOTHALAMUS OF THE RABBITS

Experiments were carried out on 18 rabbits under anesthesia of ura- thane. We recorded the single unit discharge of thermosensitive neurons with the glass micropipettes in the preoptic-anterior hypothalamus(PO-AH) of the rabbits, and observed the effect of the electro-acupuncture of the point "Dazhui" and "Quchi" on its unit discharge. The experiments showed that the electroacupuncture could increase the unit discharge of the majority (20/26) heat-sensitive neurons in the PO-AH, reduce the unit discharge of the majority (12/13) cold-sensitive neurons and had no changes with the temperature-insensitive neurons. The unit discharge changes the heat-sensitive neurons and the cold-sensitive neurons usually revive their autonomic frequency rates after stopping the acupuncture 5～8 minutes. We observed the unit of the excited effect on the electro-acupuncture in the heat-sensitive neurons. The unit discharge showed twice increase at the 11 th～12 th min. after stopping the electro-acupuncture. Its discharge rates were higher than the electro-acupuncture and lasted for 30.3 minutes(rang 11～82 minutes). The present results indicates that the electro-acupuncture could marke- dly have excitative effect on the heat-sensitive neurons and inhibitory-ef- fect on the cold-sensitive neurons.