针刺信号的立毛线传递及其交感轴突反射机制研究

在皮肤交感物质分布线和立毛肌交感神经优势支配的基础上,为探索针刺信号的传递机制,将大鼠环形剪毛后针刺或皮肤注射药物,观察立毛运动现象以及皮肤切断、去中枢神经支配等因素对立毛运动的影响.结果显示针刺后出现与皮肤交感物质分布线走行一致的立毛线,皮内注射苯肾上腺素或垂体后叶素刺激局部立毛肌的收缩后出现相似的立毛线.完全切断皮肤时立毛线被阻断,切断部分真皮没有阻断立毛线,若在切断部分真皮的切口内微量注射普鲁卡因,立毛线同样被阻断;在去中枢神经支配的皮条上也观察到立毛线的产生.这些表明针刺信号沿交感物质分布线上的毛囊立毛肌间以机械牵拉-交感神经轴突反射机制传递.

Study on the Pilomotor Line and Its Mechanism of Sympathetic Axon Reflex for the Propagation of Acupuncture Signals

On the basis of previous study that the most of adrenergic nerve endings in dermis were plexuses in arrector pili(AP) muscles along the sympathetic adrenagic substance (SAS) line, we researched the propagating mechanism of qcupuncture signals along skin. The rat's hairs were sheared as 12-16 rings from head toleg. The pilomotor was observed when acupuncture or injection of drugs at an acupoint or low back. Also the influence of cutting skin and de-innervation of nerves on the pilimortor was studied. After acupuncture a pilomotor line could be seen from low back to cheek. Injection of phenylephrine or posterior pituitary hormones along the SAS line also caused pilomotor line. When a skin strips were made by severing along the SAS line along the back of the rat, injection of phenylephrine or acupuncture at one end caused a pilomotor line through the skin strip to the another end. When skin was severed to break the SAS line, the pilomotor line did not cross the incision. When the incision only was limited in dermis, the pilomotor line did not be influenced. When the shallow incision was pretreated with injection of procaine, the pilomotor line was blocked too. As a conclusion, the propagation of acupuncture signals along skin depends on the contraction of AP muscles and was intermediated by sympathetic axon reflex though reticular dermis/hypodermis.