| 评价螺旋体乳胶快速反应实验检测梅毒血清的特异性和敏感性 |
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| 引用本文： | 晋红中,王家璧,王晓蜂,邵燕玲,何志新,刘跃华,洪少林. 评价螺旋体乳胶快速反应实验检测梅毒血清的特异性和敏感性[J]. 中国性科学, 2003, 12(1): 11-13,10 |
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| 作者姓名： | 晋红中 王家璧 王晓蜂 邵燕玲 何志新 刘跃华 洪少林 |
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| 作者单位： | 1. 北京协和医院,100730
2. 中国医学科学院中国协和医科大学 |
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| 摘 要： | 梅毒的诊断依靠临床及实验室检查。目前实验室常规进行快速血浆反应素环状卡片试验(RPR),是一种筛查试验;用死的或活的梅毒螺旋体来检测抗梅毒螺旋体抗体,包括荧光密螺旋体抗体吸收试验(FTA-ABS)和梅毒螺旋体血球凝集试验(TPHA),这两者是确诊试验。除极早期梅毒外,各期梅毒均能得到诊断。心拟脂试验(如RPR)可检测到感染3～5周后的抗体,敏感性高,但缺乏特异性,可导致假阳性结果(如自身免疫性疾病等)。螺旋体试验(FTA-ABS,TPHA)敏感
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| 关 键 词： | 评价 螺旋体 乳胶快速反应实验 检测 梅毒 血清 特异性 敏感性 |
Sensitivity and specificity of Diesse syphilis fast test in testing syphilis serum |
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| Jin Hongzhong,Wang Jiabi,Wang Xiaofeng,Shao Yanling,He Zhixin,Liu Yuehua,Hong Shaolin. Sensitivity and specificity of Diesse syphilis fast test in testing syphilis serum[J]. The Chinese Journal of Human Sexuality, 2003, 12(1): 11-13,10 |
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| Authors: | Jin Hongzhong Wang Jiabi Wang Xiaofeng Shao Yanling He Zhixin Liu Yuehua Hong Shaolin |
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| Abstract: | Objective To assess sensitivity and specificity of Diesse syphilis fast test(DSFT)in routine use,and compareit with rapid plasma reagin circle card test(RPR test),Treponema pallidum particle agglutination assay(TPHA),fluorescenttreponemal antibody absorption test(FTA-ABS test).Methods DSFT,RPR,TPHA,FTA-ABS were used to detect 500cases of syphilis and normal serum.Results Using FTA-ABS as gold standard,the sensitivity and specificity of DSFT were98.6%(204/207),and 93.2%(273/293),respectirely(x~2=1.04,P>0.05.Using TPHA as gold standard,the sensitivityand specifity of DSFT were 100%(223/223),99.6%(273/277),respectively(x~2=0.04,P>0.05).Conclusion TheDiesse syphilis fast test in routine use has high sensitivity and specificity in testing syphilis. |
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| Keywords: | Diesse syphilis fast test rapid plasma reagin cirelecard fest roeponema pallidum pastide agglutination assay flworescent trepcnemal antibody absorfionfect syphilis serum |
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