荨麻疹性血管炎临床及发病机理探讨

目的探讨荨麻疹性血管炎临床特征及发病机理。方法对１６例荨麻疹性血管炎临床及实验室检查资料进行分析。结果本病符合Ⅲ型变态反应引起的免疫复合物疾病，ＩｇＧ和补体Ｃ３在发病和皮损的形成中起了重要的作用，局部组织低垂或受压至组织液体静压增大与皮损的形成亦有密切的关系。结论本病好发于成年女性，皮损以风团和环状红斑样损害为特征，四肢关节游走性疼痛和眼结膜充血为常见的表现。

Study on the Pathogeny and Clinical Trait of Urticarial Vasculitis (Report of 16 Cases).

Objective To explore the clinical features and mechanism of urticarial vasculitis.Method Data of clinical appearence and laboratory examinations of 16 patients with urticarial vasculitis were analysed.Results The disorder was mediated by immune complex in type Ⅲ allergic reaction.Immunoglobulin G (IgG) and complement 3(C 3) might take important parts in the formation of cutaneous lesions.The urticarial wheal resulted from increased capillary pressure,which allows proteins and fluids to extravasate.Conclusion The disease is usually found in adult females.Urticarialike cruption and annular erythema are commonly seen,especially on the lower part of the extremities and the areas under pressure of trunk.The patients suffer from migratory arthralgia of limbs and conjunctiva congested.