(Auto)aggression and serotonin. A review of human data |
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Authors: | H De Cuyper |
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Institution: | Psychiatrisch Centrum Salve Mater, Lovenjoel, Belgium. |
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Abstract: | This paper reviews the main findings concerning a possible relationship between disordered serotonin metabolism and manifestations of human (auto) aggression. Most available work suggests a relationship between diminished 5-HT metabolism and suicidal behavior. Moreover, it seems warranted to hypothesize a relationship between disturbed aggression regulation and diminished central serotonin metabolism. Some major methodological shortcomings in biological suicide research--in particular focused on problems with monoamine studies--are mentioned. |
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