| 2009年流行性甲型H1N1流感重症肺炎患儿血清肺表面活性蛋白A、B、C、D的变化 |
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| 引用本文： | 舒林华,张晗,尚云晓,宗志红,相云,刘立云,刘芬,崇维琨. 2009年流行性甲型H1N1流感重症肺炎患儿血清肺表面活性蛋白A、B、C、D的变化[J]. 山东医药, 2011, 51(48): 16-18 |
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| 作者姓名： | 舒林华 张晗 尚云晓 宗志红 相云 刘立云 刘芬 崇维琨 |
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| 作者单位： | 1. 中国医科大学附属盛京医院,沈阳,110004
2. 中国医科大学 |
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| 摘 要： | 目的探讨流行性甲型H1N1流感（简称甲流）重症肺炎患儿肺表面活性蛋白A、B、C、D在血清含量变化的特点，寻找肺组织损伤的生化指标。方法采用ELISA方法检测8例甲流重症肺炎患儿（甲流组）和20例健康儿童（对照组）血清肺表面活性蛋白A、B、C、D含量，同时化验前白蛋白和白蛋白等。结果甲流组血清肺表面活性蛋白A、B、C、D含量高于对照组（P均〈0．05）；外周血白细胞、血浆前白蛋白、白蛋白等低于对照组（P均〈0．05）；二聚体高于对照组（P〈0．05）。结论甲流重症肺炎患儿血清肺表面活性蛋白A、B、C、D含量可作为肺组织损伤严重程度的检验指标。
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| 关 键 词： | 流行性甲型H1N1流感 重症肺炎 肺表面活性物质相关蛋白质类 前白蛋白 白蛋白 |
Alterations of serum pulmonary surfactant proteins in children with severe pneumonia caused by pandemic H1N1 influenza |
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| SHU Lin-hua,ZHANG Han,SHANG Yun-xiao,ZONG Zhi-hong,XIANG Yun,LIU Li-yun,LIU Fen,CHONG Wei-kun. Alterations of serum pulmonary surfactant proteins in children with severe pneumonia caused by pandemic H1N1 influenza[J]. Shandong Medical Journal, 2011, 51(48): 16-18 |
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| Authors: | SHU Lin-hua ZHANG Han SHANG Yun-xiao ZONG Zhi-hong XIANG Yun LIU Li-yun LIU Fen CHONG Wei-kun |
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| Affiliation: | SHU Lin-hua1,ZHANG Han,SHANG Yun-xiao,ZONG Zhi-hong,XIANG Yun,LIU Li-yun,LIU Fen,CHONG Wei-kun(1 Shengjing Hospital,China Medical University,Shenyang 110004,P.R.China) |
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| Abstract: | Objective To explore the alterations of pulmonary surfactant protein-A,B,C and D in serum in children with severe pneumonia caused by 2009 pandemic H1N1 influenza virus.Method Serum pulmonary surfactant protein-A,B,C and D were measured in 8 severe H1N1 pneumonia children and 20 healthy children with ELISA as well as peripheral white blood cells,prealbumin and albumin.Results Serum levels of pulmonary surfactant protein-A,B,C and D in severe H1N1 pneumonia children were significantly increased compared with... |
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| Keywords: | pandemic H1N1 influenza pulmonary surfactant-associated proteins prealbumin albumin |
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