抗病毒饮方药及其煎剂中微量元素含量及溶出率测定

目的测定抗病毒饮方药及其煎剂中Ca、Mg、Mn、Cu、Fe、Zn等元素的含量,从而计算出各元素的溶出率,考察提取工艺的合理性。方法采用火焰原子吸收光谱法。结果抗病毒饮方药及其煎剂中Ca、Fe的含量最高,Mg在其次,再次是Mn、Zn,Cu的含量最低;所测6种元素中Mg的溶出率最高,可达90.36%;Cu则偏低,仅0.59%;其余4种元素溶出率大多数在50～70%。两个不同浓度煎剂的6种元素溶出率无显著性差异(P>0.05)。结论煎煮法提取工艺基本合理,尚有待进一步提高。

Determination of the Content and Dissolution Rate of Trace Elements in Antivirus Formula and Its Extract

Objective To determine the content of Ca,Mg,Mn,Cu,Fe and Zn in Anti-virus Formula and its extract,and to calculate their dissolution rate and evaluate the rationality of the extract process technology. Methods Flame atomic absorption spectrometry was used. Results In Anti-virus Formula and its extract,the contents of Ca,Fe were the highest,Mg came the second,Mn,Zn were lower than Mg,and Cu was the lowest. Of the 6 trace elements,the dissolution rate of Mg was 90.36 %,Cu was only 0.59 %,and that of the other four elements were in the range of 50 %to 70 %. The dissolution rate of the extracts at different concentrations had no significant difference (P>0.05). Conclusion The extract technology is basically reasonable,and need further improvement.