结肠癌同时性肝转移同期手术与分期手术的疗效比较

目的：对比结肠癌同时性肝转移行同期手术与分期手术切除转移灶的疗效。方法：回顾性分析36例结肠癌同时性肝转移患者的临床资料，其中16例行结肠癌根治术同时切除肝转移病灶（同期手术组）；20例先行结肠癌根治性切除、二期行肝转移病灶切除（分期手术组）。比较两组患者的1，3，5年生存率。结果：同期手术组患者1，3，5年生存率分别为87.5%，37.5%，18.8%，分期手术组患者1，3，5年生存率分别为65%，10.0%，0.0%。两组比较，1年生存率差异无统计学意义（P>0.05），同期手术组3，5年生存率明显高于分期手术组（均P<0.05）。结论：结肠癌同时性肝转移行同期手术可延长患者生存时间。

Simultaneous versus staged resection for synchronous liver metastases from colon cancer

Objective: To compare the clinical efficacy of simultaneous and staged resection for colon cancer with synchronous liver metastases. Methods: The clinical data of 36 patients with synchronous liver metastases from colon cancer were retrospectively analyzed. Of the patients, 16 cases underwent radical resection of colon cancer and simultaneous resection of liver metastases (simultaneous resection group), and the other 20 cases underwent radical resection of colon cancer and two-stage resection of liver metastases (staged resection group). The 1-, 3- and 5-year survival rates between the two groups were compared. Results: The 1-, 3-, and 5-year survival rate in simultaneous resection group was 87.5%, 37.5% and 18.8%, and in staged resection group was 65%, 10.0% and 0.0%, respectively. By comparison, the 1-year survival rates had no statistical difference between the two groups (P>0.05), but both 3- and 5-year survival rates in simultaneous resection group were significantly higher than those in staged resection group (both P<0.05). Conclusion: Simultaneous surgery can prolong the survival time of patients with synchronous liver metastases from colon cancer.