胃癌根治联合胰十二指肠切除治疗局部进展期胃癌疗效分析：附11例报告

目的：探讨联合行胃癌根治及胰十二指肠切除治疗局部进展期胃癌的疗效。 方法：回顾性分析2005年5月—2012年6月期间11例因侵及胰头或十二指肠而联合行胃癌根治及胰十二指肠切除术的胃癌患者的临床资料。 结果：行远端胃联合胰十二指肠切除术6例，行远端胃联合胰十二指肠切除加右半结肠切除5例，全组无手术死亡病例。术后并发症4例，其中胆瘘1例，胰瘘1例，腹腔感染1例，切口感染1例。患者术后1，3，5年生存率分别为68.2%，34.1%，22.7%。 结论：对能达到R0切除的胃癌侵犯胰头或十二指肠患者，行胰十二指肠切除术是积极有效的治疗方法。

Gastrectomy plus pancreaticoduodenectomy for locally advanced gastric cancer: a report of 11 cases

Objective: To investigate the efficacy of gastrectomy plus pancreaticoduodenectomy (PD) in treatment of locally advanced gastric cancer. Methods: The clinical data of 11 patients with stomach cancer undergoing gastrectomy plus PD due to pancreatic head or duodenal involvement during May 2005 to Jun 2012 were retrospectively analyzed. Results: Of the patients, 6 cases underwent distal subtotal gastrectomy with simultaneous PD, and 5 cases underwent distal subtotal gastrectomy plus PD and right hemicolectomy. No death occurred in the whole group of patients, and postoperative complications occurred in 4 cases, of whom, one case had biliary fistula, one had pancreatic fistula, one had intra-abdominal infection and one had wound infection. The 1-, 3- and 5-year survival rates were 68.2%, 34.1% and 22.7%, respectively. Conclusion: For stomach cancer patients with pancreaticoduodenal involvement, gastrectomy plus PD is an effective procedure as long as an R0 resection can be achieved.